Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors
نویسندگان
چکیده
منابع مشابه
Temperature Tunability of Dielectric/ Liquid Crystal / Dielectric Photonic Crystal Structures
Recently, photonic crystals doped with liquid crystal (LC) material havegained much research interest. In this article new ternary one-dimensional photoniccrystal introduced and studied. The liquid crystal layer of 5CB and 5PCH is sandwichedby two dielectric layers. For the first time, we use four structures SiO2/UCF35/CaF2,SiO2/5CB/CaF2, NFK51/UCF35/NPSK53 and NFK51/5CB/NPSK53. The effect ofte...
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Dengue viruses (DVs) are responsible for the most medically relevant arboviral diseases. However, the molecular interactions mediating DV entry are poorly understood. We determined that TIM and TAM proteins, two receptor families that mediate the phosphatidylserine (PtdSer)-dependent phagocytic removal of apoptotic cells, serve as DV entry factors. Cells poorly susceptible to DV are robustly in...
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Giardiasis is an important human parasitic disease. Giardia is a genus composed of binuclear flagellate protozoa. Giardia duodenalis is a parasitic species for a wide range of vertebrates, including humans. Heterogeneity in G. duodenalis has been shown by serological, biochemical, and molecular analysis. In the present study, the possible genetic similarity between Giardia in sheep and humansan...
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Exosomes, 30-200 nm nanostructures secreted from donor cells and internalized by recipient cells, can play an important role in the cellular entry of some viruses. These microvesicles are actively secreted into various body fluids, including blood, urine, saliva, cerebrospinal fluid, and breast milk. We successfully isolated exosomes from human breast milk and plasma. The size and concentration...
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In this study, a cellular surface membrane protein of immunoglobulin (Ig) superfamily (IgSF) was identified from a human dendritic cell (DC) cDNA library by large-scale random sequencing, which is identical to previously reported Tim-3 (T-cell Ig- and mucin-domain-containing molecule 3). Recent data have suggested the association of the 281-residue mouse Tim-3 molecule with Th1-related T cell r...
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ژورنال
عنوان ژورنال: Chinese Science Bulletin
سال: 2015
ISSN: 0023-074X
DOI: 10.1360/n972015-01255